Inherited predisposition to multiple myeloma
نویسندگان
چکیده
منابع مشابه
Inherited predisposition to glioma.
In gliomas, germline gene alterations play a significant role during malignant transformation of progenitor glial cells, at least for families with occurrence of multiple cancers or with specific hereditary cancer syndromes. Scientific evidence during the last few years has revealed several constitutive genetic abnormalities that may influence glioma formation. These germline abnormalities are ...
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Myeloid neoplasms include myelodysplastic/ myeloproliferative neoplasms (MDS/MPN) and acute myeloid leukemia (AML). While majority of these disorders are still sporadic, it is becoming clear that a subset of them have a germline predisposition and is familial in nature. With the advancement and integration of molecular studies, it has been recognized that approximately 5-10% of hematological ma...
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ژورنال
عنوان ژورنال: Therapeutic Advances in Hematology
سال: 2013
ISSN: 2040-6207,2040-6215
DOI: 10.1177/2040620713485375